Objective To understand the relationship between temperature and blood pressure in north part and south part of China，and provide the scientific basis for making relative intervention measures. Methods The blood pressure data were from "China Chronic Disease and Risk Factor Surveillance in 2018"，the multi-stage stratified cluster random sampling method was used to select the residents （≥18 years old） in China as the subjects （116 368 cases），the investigation was performed with face-to-face questionnaire，physical measurement and laboratory examination. The data of temperature were form reanalysis data of ERA5. Analysis of variance，single factor linear regression，Kruskal-Wallis H test and multivariate linear regression were used to analyze data;the restricted cubic spline （RCS） was used to draw curve of exposure response between temperature and blood pressure. Results The average systolic blood pressure （SBP） and diastolic blood pressure （DBP） in 2018 were （125.4±17.3） mm Hg and （75.8±10.7） mm Hg;the average SBP and DBP in residents of north China were significantly higher than those in residents of south China （P<0.01）. The restricted cubic spline of exposure response between temperature and blood pressure showed that in north China there was a linear negative relationship between temperature and SBP，but there was a U relationship between temperature and DBP;however in south China there was the nolinear negative relationship between temperature and SBP or DBP.The multivariate linear regression analysis showed that in south China as compared with temperature ≥18 ℃，the SBP and DBP in residents with temperature <10 ℃ （β values were 3.67 and 2.11），the temperature 10-<14 ℃ （β values were 2.23 and 1.21），the temperature 14-<18 ℃ （β values were 1.62 and 1.30） were significantly higher （P<0.05 or P<0.01）. Conclusion The blood pressure in adults of north China is higher than that of south China，there is difference of the relationship between temperature and blood pressure. In extreme temperature （especially extreme low temperature），the measures should be taken to increase the rate of blood pressure detection，and to promote the maintenance of normal blood pressure in different areas.

Objective To construct a priority decision-making model for hypertension prevention and control，determine the priority of hypertension prevention and control measures，and provide the basis for decision-making in the development of hypertension prevention and control in various regions. Methods All 488 districts，which were rated as national-level comprehensive prevention and control demonstration areas for chronic diseases，were selected as the investigation areas. The business backbone of chronic disease prevention and control majors in each district center for disease control and prevention filled out the questionnaires. The information on the importance and accessibility of hypertension prevention and control measures was collected. The Importance-Performance Analysis （IPA） model was used to divide the dimensional indicators of hypertension prevention and control into quadrants. The standardized factor loading coefficients of confirmatory factor analysis were used to rank the dimensional indicators in the same quadrant. The discrimination index of item response theory was used to prioritize the action items. Statistical analysis software was R 4.0. Results The study actually collected 468 valid questionnaires. The analysis results of the IPA model of the accessibility-importance of hypertension prevention and control dimensions showed that in the highest priority quadrant，the priority of each dimension indicator was policy formulation，system construction，and standardized management of communities. The dimensional indicator of the second improvement quadrant was environmental support，and the dimensional indicator of the lowest priority quadrant was monitoring and evaluation.Also the specific measures within the same dimension indicators in combination with the discrimination were sorted. Among all measures，the three measures with the highest priority were moderate exercise，weight control and reasonable diet measures in lifestyle interventions.From different dimensions，the implementation of the first-diagnosis blood pressure measurement system for people （>35 years old） was the highest prioritized measure in the dimension of policy formulation，the building of the hypertension management team was the highest prioritized measure in system construction，the moderate exercise was the highest prioritized measure in standardized community management，and the community health education was the highest prioritized measure in environmental support. Conclusion For scoring the importance and accessibility of hypertension prevention and control measures，a priority decision-making model is constructed to provide decision-making basis for local hypertension prevention and control.

Objective To explore the relationship between the triglyceride glucose product index （TyG） and hypertension risk，and provide the scientific basis for the prevention and treatment of hypertension. Methods The data were from the natural population cohort of Guizhou Province established in 2010. A multi-stage stratified random cluster sampling method was used in the cohort，and 9 280 residents from 48 towns and townships in 12 counties （cities and districts） were investigated. A follow-up investigation was completed from 2016 to 2020. Subjects with lost follow-up，baseline hypertension，and missing data of baseline blood pressure，triglyceride and fasting blood glucose were excluded. Finally，5 504 baseline subjects were included in the analysis. Subjects with triglyceride and fasting glucose deficiency at follow-up were excluded. A total of 4 367 subjects were included as dynamic subgroups. The baseline investigation and following-up investigation included the questionnaires，physical examination，and laboratory tests to measure triglyceride （TG） and fasting blood glucose （FPG），and to calculate the triglyceride glucose product index （TyG）. The t test，one-way analysis of variance， χ² test，and Cox risk proportion model analysis were used to analyze the data.The dose-response relationship between TyG and the risk of hypertension was observed using restricted cubic spline plots. The used software was SPSS 21.0. Results Cox risk proportion model analysis showed that after adjusting for confounding factors，as compared with normal baseline TyG group，the hypertension risk of baseline high TyG group increased by 23.1%（HR=1.231， 95%CI：1.037-1.461）;as compared with the group keeping normal TyG，the hypertension risk in the group with normal elevation and in the group with continual-elevation increased by 51.0%（HR=1.510，95%CI：1.286-1.772） and 59.8%（HR=1.598，95%CI：1.202-2.126），respectively. As compared with the group in which TyG increased 0~<1，the risk of hypertension of groups in which TyG increased 1-<2 and ≥2 increased by 37.8%（HR=1.378，95%CI：1.139-1.668） and 130.5%（HR=2.305，95%CI：1.637-3.246）. The results of restricted cubic spline plots showed a non-linear dose-response relationship between baseline TyG，TyG changes and the hypertension risk. Conclusion TyG is an independent risk factor for hypertension. Excessive TyG or the gradual increase of TyG will increase the risk of hypertension. The risk of hypertension can be reduced by controlling FPG and triglyceride.

目的 了解中国1990—2019年结核病疾病负担情况及其发展趋势，为结核病防治策略的完善提供参考。方法 利用2019年全球疾病负担数据库，提取中国1990—2019年结核病发病、死亡、患病、伤残调整寿命年（DALY）等数据并计算其标化率，采用Joinpoint 4.9.0.0软件利用Joinpoint回归模型分析变化趋势。结果 Joinpoint回归分析结果显示，1990—2019年中国结核病标化发病率、标化死亡率、标化DALY率、标化患病率均呈下降趋势，变化趋势均有统计学意义（P<0.05）。其中，标化发病率总体年均下降3.2%，男性年均下降2.6%，女性年均下降4.0%;标化死亡率总体年均下降7.8%，男性年均下降7.2%，女性年均下降8.7%;标化患病率总体年均下降0.9%，男性年均下降0.9%，女性年均下降1.0%;标化DALY率总体年均下降7.5%，男性年均下降7.0%，女性年均下降8.4%，以上变化趋势均有统计学意义（P<0.05）。Joinpoint回归分析组间比较结果显示，男性、女性各项疾病负担指标变化趋势比较，差异均有统计学意义（P<0.05）。结论 1990—2019年中国结核病疾病负担有所下降，结核病防治效果显著，但患病率仍较高，今后还需多举措加大结核病防治力度，完善结核病防治策略。